二氢羊毛甾醇 24,25-二氢羊毛甾醇醇

二氢羊毛甾醇

 24,25-二氢羊毛甾醇醇          CAS  911660-54-3         分子量428.73        分子式：C30H52O

纯       度：     HPLC95%
物理性状：     白色粉末
检测方法：      高效液相（HPLC）质谱（Mass) 核磁（NMR)
用      途：      仅供研究使用,不得用于医学诊断。
包      装：      5mg~1g 棕色玻璃瓶。
储存条件：     贮存在避光密闭容器中，冷藏或者冷冻长期保存。
样品溶液现配现用。如果特殊情况需要提前配制的话，最好分成独立包装冷冻保存（-20℃以下），临用前再取出解冻，通常可以保存2周。

来源
羊毛脂。

Description

• low-toxicity and high-yielding method for the production of pure lanosterol and dihydrolanosterol from the commercially available mixture. Optimum conditions are presented for the one-pot production of the intermediate 24,25 vicinal diol of lanosterol acetate (via either epoxidation or hydroxyhalogenation) which is readily separated from the unreacted dihydrolanosterol acetate. The lanosterol diol can then be converted to pure (>97%) lanosterol. Hypophosphorous acid was used for both the conversion of the epoxide to the diol, and as a catalyst for the hydroxyhalogenation by N-halosuccinimides of the olefinic bond

References

• [1]. Kavtaradze LK, Manley-Harris M, Nicholson BK. A low-toxicity method for the separation of lanosterol and dihydrolanosterol from commercial mixtures.. PMID: 15465116